Posted: June 15th, 2015 | Author: Sven | Filed under: found on the net, Research Data | Tags: articles, costs, journals, reproducibility | Comments Off on Article: The Economics of Reproducibility in Preclinical Research
In 2012, an estimated 114.8 billion $ in the US were spent on life sciences research. Roughly half of it is spent on preclinical research, with government sources providing the majority of funding – approximatly 38 billion US$.
Now, three researchers calculate the costs of irreproducible research in preclinical research near 28 billion $ – only for the United States alone. That is the conclusion of a study published in PLoS Biology a few days ago.
In the opinion of the study’s authors, the giant amount of 28 billion $ accumulates, because low reproducibility rates within life science research undermine cumulative knowledge production and contribute to both delays and costs of therapeutic drug development.
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Posted: November 6th, 2014 | Author: Sven | Filed under: found on the net | Tags: Replication, reproducibility | Comments Off on Biomedical Sciences: Journals unite to forster reproducible research
When it comes to the topic of replication, it always is a good idea to consult the webpages of the nature journal. Yesterday, for instance, the journal reported that a group of editors representing more than 30 major journals, representatives from funding agencies as well as scientific leaders discussed principles and guidelines for preclinical biomedical research in June 2014.
The gathering was convened by the US National Institutes of Health, Nature and Science.
The attendees agreed on a common set of principles and guidelines in reporting preclinical research that list proposed journal policies and author reporting requirements in order to promote transparency and reproducibility. Read the rest of this entry »
Posted: April 30th, 2013 | Author: Sven | Filed under: found on the net | Tags: nature, Replication, reproducibility | Comments Off on New Nature Special: Challenges in irreproducible Research
nature has published a new special issue on challenges in irreproducible research. The journal addresses the challenges and barriers of reproducibel research:
No research paper can ever be considered to be the final word, and the replication and corroboration of research results is key to the scientific process. In studying complex entities, especially animals and human beings, the complexity of the system and of the techniques can all too easily lead to results that seem robust in the lab, and valid to editors and referees of journals, but which do not stand the test of further studies. Nature has published a series of articles about the worrying extent to which research results have been found wanting in this respect. The editors of Nature and the Nature life sciences research journals have also taken substantive steps to put our own houses in order, in improving the transparency and robustness of what we publish. Journals, research laboratories and institutions and funders all have an interest in tackling issues of irreproducibility. We hope that the articles contained in this collection will help.
All articles within this issue are available free of charge. The table of contents is available here.
Graphic: pasukaru76, www.flickr.com